Education
1997 - 1999
1997 - 1999Doctorate
Bursa Uludağ University, SAĞLIK BİLİMLERİ ENSTİTÜSÜ, Tıbbi Biyoloji (Dr), Turkey
1990 - 1993
1990 - 1993Postgraduate
Bursa Uludağ University, FEN BİLİMLERİ ENSTİTÜSÜ, Biyoloji (Yl) (Tezli), Turkey
1986 - 1990
1986 - 1990Undergraduate
Bursa Uludağ University, FEN-EDEBİYAT FAKÜLTESİ, Biyoloji Bölümü, Turkey
Research Areas
Health Sciences
Natural Sciences
Academic Positions
2009 - Present
2009 - PresentProfessor
Bursa Uludağ University, TIP FAKÜLTESİ, TEMEL TIP BİLİMLERİ
2003 - 2009
2003 - 2009Associate Professor
Bursa Uludağ University, TIP FAKÜLTESİ, TEMEL TIP BİLİMLERİ
Managerial Experience
2022 - 2026
2022 - 2026Department Academic Incentive Evaluation Commission Member
Bursa Uludağ University, Tıp Fakültesi, Temel Tıp Bilimleri
2015 - 2018
2015 - 2018Director of Vocational School
Bursa Uludağ University
Courses
Articles
2025
20251. Prognostic Significance of mTOR Expression in Recurrence Following Hepatic Metastasectomy in Colorectal Cancer
Aksoy F., Ak-Aksoy S., Karamustafaoglu A., Tekin C., Ercelik M., Tunca B., et al.
LIFE-BASEL
, vol.15, no.6, 2025 (SCI-Expanded)
2025
20252. Oleuropein- and hydroxytyrosol-loaded nanoparticles: a novel strategy against glioblastoma aggressiveness
ERÇELİK M., Tekin C., Pamukcu A., Gurbuz M., Karaman D. S., TUNCA B.
Naunyn-Schmiedeberg's Archives of Pharmacology
, 2025 (SCI-Expanded)
2025
20253. Matrix metalloproteinase-7 and matrix metalloproteinase-9 expression is upregulated in congenital lung malformations
Parlak A., Aksoy S., Ercelik M., Tekin C., Nazlioglu H. O., Tunca B., et al.
TURKISH JOURNAL OF PEDIATRICS
, no.1, pp.31-38, 2025 (SCI-Expanded)
2024
20244. A new nano approach to prevent tumor growth in the local treatment of glioblastoma: Temozolomide and rutin-loaded hybrid layered composite nanofiber
Ercelik M., Tekin C., Gurbuz M., Tunçbilekli Y., Dogan H. Y., Mutlu B., et al.
Asian Journal of Pharmaceutical Sciences
, vol.19, no.6, 2024 (SCI-Expanded)
2024
20245. Leaf Extract from European Olive (Olea europaea L.) Post-Transcriptionally Suppresses the Epithelial-Mesenchymal Transition and Sensitizes Gastric Cancer Cells to Chemotherapy
Tekin C., Ercelik M., Dunaev P., Galembikova A., Tezcan G., Aksoy S., et al.
Biochemistry (Moscow) , vol.89, pp.97-115, 2024 (SCI-Expanded)
2024
20246. Leaf Extract from European Olive (Olea europaea L.) Post-Transcriptionally Suppresses the Epithelial-Mesenchymal Transition and Sensitizes Gastric Cancer Cells to Chemotherapy
Tekin C., Ercelik M., Dunaev P., Galembikova A., TEZCAN G., AKSOY S., et al.
BIOCHEMISTRY-MOSCOW
, vol.89, no.1, pp.97-115, 2024 (SCI-Expanded)
2016
20167. Circulating miR-195 as a therapeutic biomarker in turkish breast cancer patients
ÇEÇENER G., Ak S., Eskiler G. G., Demirdogen E., ERTÜRK BAKIR E., GÖKGÖZ M. Ş., et al.
Asian Pacific Journal of Cancer Prevention
, vol.17, no.9, pp.4241-4246, 2016 (Scopus)
2015
20158. BRCA mutations cause reduction in miR-200c expression in triple negative breast cancer
ERTÜRK BAKIR E., ÇEÇENER G., TEZCAN G., EGELİ Ü., TUNCA B., Gokgoz S., et al.
GENE
, vol.556, no.2, pp.163-169, 2015 (SCI-Expanded)
2014
20149. BRCA1/2 Germline Mutations and Their Clinical Importance in Turkish Breast Cancer Patients
ÇEÇENER G., EGELİ Ü., TUNCA B., ERTÜRK BAKIR E., AKSOY S., Gokgoz S., et al.
CANCER INVESTIGATION
, vol.32, no.8, pp.375-387, 2014 (SCI-Expanded)
2014
201410. Expression status of let-7a and miR-335 among breast tumors in patients with and without germ-line BRCA mutations
ERTÜRK BAKIR E., ÇEÇENER G., EGELİ Ü., TUNCA B., TEZCAN G., Gokgoz S., et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY
, vol.395, no.1-2, pp.77-88, 2014 (SCI-Expanded)
2014
201411. Evaluation of microRNA expression profiles in triple-negative (ER, PR and Her2/neu) breast cancer patients with and without germ-line BRCA mutations
ERTÜRK BAKIR E., ÇEÇENER G., EGELİ Ü., TUNCA B., TEZCAN G., Gokgoz S., et al.
EUROPEAN JOURNAL OF CANCER
, vol.50, 2014 (SCI-Expanded)
2014
201412. Molecular Markers for Patients with Thymic Malignancies: not Feasible at Present?
Avci N., ÇEÇENER G., DELİGÖNÜL A., ERTÜRK BAKIR E., TUNCA B., EGELİ Ü., et al.
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
, vol.15, no.8, pp.3457-3460, 2014 (SCI-Expanded)
2014
201413. Evaluation of Genetic Variations in miRNA-Binding Sites of BRCA1 and BRCA2 Genes as Risk Factors for the Development of Early-Onset and/or Familial Breast Cancer
ERTÜRK BAKIR E., ÇEÇENER G., POLATKAN S. A. V., Gokgoz S., EGELİ Ü., TUNCA B., et al.
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION
, vol.15, no.19, pp.8319-8324, 2014 (SCI-Expanded)
2013
201314. Microsatellite instability status affects gene expression profiles in early onset colorectal cancer patients
AKSOY S., TUNCA B., Yilmazlar T., TEZCAN G., ÇEÇENER G., EGELİ Ü., et al.
JOURNAL OF SURGICAL RESEARCH
, vol.185, no.2, pp.626-637, 2013 (SCI-Expanded)
2012
201215. The Promoter Hypermethylation Status of GATA6, MGMT, and FHIT in Glioblastoma
ÇEÇENER G., TUNCA B., EGELİ Ü., BEKAR A., TEZCAN G., ERTÜRK BAKIR E., et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY
, vol.32, no.2, pp.237-244, 2012 (SCI-Expanded)
2012
201216. CK19, CK20, EGFR and HER2 status of circulating tumor cells in patients with breast cancer
TUNCA B., EGELİ Ü., ÇEÇENER G., TEZCAN G., Gokgoz S., Tasdelen L., et al.
TUMORI JOURNAL
, vol.98, no.2, pp.243-251, 2012 (SCI-Expanded)
Books
2024
20241. BEYİN TÜMÖRLERİNİN TEDAVİSİNDE YENİ BİR YAKLAŞIM: SENESENS
Erdoğan A., Erçelik M., Gürbüz M., Tekin Ç., Tunca B.
in: Sağlık Bilimlerinde Güncel Araştırmalar-2024, Assoc. Prof. Dr. Leyla TEKİN,Prof. Dr. Halit DEMİR, Editor, Livre.net , Lyon, pp.19-40, 2024
2024
20242. DİYABET, KARACİĞER HASTALIKL ARI VE EPİGENETİK SÜREÇLER
Yıldız T. N., Beyler B., Tekin Ç., Erçelik M., Tunca B.
in: Sağlık Bilimlerinde Güncel Araştırmalar-2024, Leyla TEKİN,Halit DEMİR, Editor, Livre.net , Lyon, pp.319-350, 2024
2024
20243. Olve leave extracts and components as an innovative approach for cancer therapy
Erçelik M., Tekin Ç., Tunca B.
in: Advances in Nanotechnology, Melis Erçelik,Çagla Tekin,Berrin Tunca, Editor, NOVA Science Publishers Inc. , New York, pp.223-278, 2024
2010
20104. Frame-shift Mutation: Genetics, Immunology and Drug Effects
Tunca B.
in: Advances in Genetics Research , Kevin V. Urbano, Editor, Nova Biomedical Books , Massachusetts, pp.137-142, 2010
2005
20055. Meme kanserinde rolü olan onkogenler ve büyüme faktörleri
Tunca B.
in: 2000’li yıllarda Meme Kanserleri-Tanı ve tedavide temel ilkeler ve uygulamalar , Prof. Dr. Kayıhan Engin, Editor, Nobel Tıp Kitapevi, Adana, pp.61-68, 2005
2003
20036. Baş-Boyun kanserlerinde moleküler temeli
Tunca B., Egeli Ü.
in: Baş-Boyun kanserlerinde moleküler biyoloji, Kayıhan Engin,Levent Erişen, Editor, Nobel Tıp Kitapevi, Adana, pp.47-57, 2003
2001
20017. Akciğer kanserinde rolü olan onkogenler ve büyüme faktörleri
Tunca B.
in: 2000’li yıllarda Akciğer Kanserleri “Tanı ve tedavide temel ilkeler ve uygulamalar”, Prof. Dr. Kayıhan Engin,Prof. Dr. Nihat Özyardımcı, Editor, Uludağ Onkoloji Yayınları dizisi , İstanbul, pp.40-46, 2001
Patent
2016
2016Olea europaea nın yapraklarından elde edilen özütün (OLE) kanser kök hücrelerinin tedavisinde kullanımı.
Patent
Registered / Approved, The Invention Registration Number: TR 2014 07670 B , Standard Registration
Scientific Project Refereeing
December 2024
December 2024TUBITAK Project
1002 - Quick Support Program, TÜBİTAK, Turkey
December 2024
December 2024TÜBİTAK International Bilateral Joint Cooperation Program Project
2535 TÜBİTAK-IRAN MSRT, TÜBİTAK, Iran
December 2024
December 2024TÜBİTAK International Bilateral Joint Cooperation Program Project
2535 TÜBİTAK-IRAN MSRT, TÜBİTAK, Iran
December 2024
December 2024TÜBİTAK International Bilateral Joint Cooperation Program Project
2535 TÜBİTAK-IRAN MSRT, TÜBİTAK, Iran
December 2024
December 2024TUBITAK Project
1501 - Industry R & D Projects Support Program, TÜBİTAK, Turkey
November 2024
November 2024TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, TÜBİTAK, Turkey
November 2024
November 2024TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, TÜBİTAK, Turkey
November 2024
November 2024TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, TÜBİTAK, Turkey
November 2024
November 2024TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, TÜBİTAK, Turkey
November 2024
November 2024TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, TÜBİTAK, Turkey
November 2024
November 2024TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, TÜBİTAK, Turkey
September 2024
September 2024TÜBİTAK International Bilateral Joint Cooperation Program Project
Romanian The National Authority for Scientific Research, ANCS Bilateral Cooperation Program, TÜBİTAK, Romania
September 2024
September 2024TÜBİTAK International Bilateral Joint Cooperation Program Project
Romanian The National Authority for Scientific Research, ANCS Bilateral Cooperation Program, TÜBİTAK, Turkey
September 2024
September 2024TÜBİTAK International Bilateral Joint Cooperation Program Project
Romanian The National Authority for Scientific Research, ANCS Bilateral Cooperation Program, TÜBİTAK, Romania
July 2024
July 2024TÜBİTAK International Bilateral Joint Cooperation Program Project
Tunisia Ministry of Higher Education and Scientific Research Bilateral Joint Cooperation Program, TÜBİTAK, Tunisia
July 2024
July 2024TÜBİTAK International Bilateral Joint Cooperation Program Project
Tunisia Ministry of Higher Education and Scientific Research Bilateral Joint Cooperation Program, TÜBİTAK, Tunisia
July 2024
July 2024TÜBİTAK International Bilateral Joint Cooperation Program Project
Tunisia Ministry of Higher Education and Scientific Research Bilateral Joint Cooperation Program, TÜBİTAK, Tunisia
July 2024
July 2024TÜBİTAK International Bilateral Joint Cooperation Program Project
Tunisia Ministry of Higher Education and Scientific Research Bilateral Joint Cooperation Program, TÜBİTAK, Tunisia
May 2024
May 2024TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, TÜBİTAK, Turkey
May 2024
May 2024TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, TÜBİTAK, Turkey
May 2024
May 2024TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, TÜBİTAK, Turkey
February 2024
February 2024TUBITAK Project
3501 - National Young Researcher Career Development Program, TÜBİTAK, Turkey
January 2024
January 2024R&D Project of Group B
TÜSEB, Turkey
December 2023
December 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
December 2023
December 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
December 2023
December 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
November 2023
November 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
November 2023
November 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
November 2023
November 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
November 2023
November 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
November 2023
November 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
October 2023
October 2023TUBITAK Project
3501 - National Young Researcher Career Development Program, Bursa Uludağ University, Turkey
September 2023
September 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
August 2023
August 2023TUBITAK Project
3501 - National Young Researcher Career Development Program, Bursa Uludağ University, Turkey
August 2023
August 2023TÜBİTAK International Bilateral Joint Cooperation Program Project
TÜBİTAK 2517 International Bilateral Cooperation, Bursa Uludağ University, Turkey
July 2023
July 2023TUBITAK Project
1002 - Quick Support Program, Bursa Uludağ University, Turkey
July 2023
July 2023TUBITAK Project
1002 - Quick Support Program, Bursa Uludağ University, Turkey
June 2023
June 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
June 2023
June 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
June 2023
June 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
June 2023
June 2023TUBITAK Project
1002 - Quick Support Program, Bursa Uludağ University, Turkey
June 2023
June 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
June 2023
June 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
June 2023
June 2023TUBITAK Project
1001 - Program for Supporting Scientific and Technological Research Projects, Bursa Uludağ University, Turkey
May 2023
May 2023TUBITAK Project
3501 - National Young Researcher Career Development Program, Bursa Uludağ University, Turkey
April 2023
April 2023TUBITAK Project
3501 - National Young Researcher Career Development Program, Bursa Uludağ University, Turkey
February 2023
February 2023TUBITAK Project
2218 - Yurt İçi Doktora Sonrası Araştırma Burs Programı, Bursa Uludağ University, Turkey
January 2023
January 2023TUBITAK Project
3501 - National Young Researcher Career Development Program, Bursa Uludağ University, Turkey
January 2023
January 2023