CK19, CK20, EGFR and HER2 status of circulating tumor cells in patients with breast cancer

Tunca B., Egeli Ü., Çeçener G., Tezcan G., Gokgoz S., Tasdelen L., ...Daha Fazla

TUMORI JOURNAL, cilt.98, sa.2, ss.243-251, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 98 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1700/1088.11937
  • Dergi Adı: TUMORI JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.243-251
  • Anahtar Kelimeler: breast cancer, circulating tumor cells, prognosis, RNA-POSITIVE CELLS, POLYMERASE-CHAIN-REACTION, MAMMAGLOBIN MESSENGER-RNA, TRANSCRIPTION-PCR ASSAY, PERIPHERAL-BLOOD, COLORECTAL-CANCER, MOLECULAR-DETECTION, PROGNOSTIC VALUE, RT-PCR, ADJUVANT CHEMOTHERAPY
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Aims and background. The major cause of death in breast cancer patients is metastasis. Various biomarkers have been used for the early detection of circulating tumor cells in the peripheral blood of breast cancer patients. The aims of the current study were to analyze circulating tumor cells in the blood of breast cancer patients by investigating EGFR, CK19, CK20 and HER2 expression profiles and to evaluate their prognostic importance.