Determination of tetracycline residues in chicken meat by liquid chromatography-tandem mass spectrometry

Cetinkaya F., Yibar A., Soyutemiz G. E., Okutan B., Ozcan A., Karaca M. Y.

FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE, cilt.5, sa.1, ss.45-49, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Sayı: 1
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1080/19393210.2012.655782
  • Dergi Adı: FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.45-49
  • Anahtar Kelimeler: meat, veterinary drug residues, veterinary drug residues - antibiotics, veterinary drug residues - tetracycline, veterinary drug residues - chloramphenicol, POULTRY MUSCLE, ANTIBIOTICS, HONEY
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Analysis of residual levels of tetracyclines (TCs) in chicken meat was performed using a validated liquid chromatography coupled with a tandem mass spectrometry (LC-MS/MS) technique. Overall, the recoveries for TCs ranged from 56.9% to 101.2%, with standard deviations of 4.5-13.2%. Detection limits ranged from 7.9 to 14.6 mu g kg(-1). In four of 60 samples, doxycycline (DXC) was determined in a range from 19.9 to 35.6 mu g kg(-1); and in one sample tetracycline was detected at 17.2 mu g kg(-1). Chlortetracycline (CTC) and oxytetracycline (OTC) were not detected in any of the tested samples. This study indicates that chicken meat sold in Bursa, Turkey, contained some residues of TCs. Therefore, stricter regulations for the use of antibiotics in the poultry industry and the monitoring of drug residues in chicken meat prior to marketing are needed. Finally, this method has been applied successfully for the confirmation of TCs in chicken meat.