Nutritional approaches in the risk reduction and management of Alzheimer's disease


Mi W., van Wijk N., CANSEV M., Sijben J. W. C. , Kamphuis P. J. G. H.

NUTRITION, vol.29, no.9, pp.1080-1089, 2013 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 29 Issue: 9
  • Publication Date: 2013
  • Doi Number: 10.1016/j.nut.2013.01.024
  • Journal Name: NUTRITION
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1080-1089
  • Keywords: Nutritional intervention, Synapse formation, Synapse function, Fortasyn Connect, Souvenaid, MILD COGNITIVE IMPAIRMENT, LONG-CHAIN OMEGA-3-FATTY-ACIDS, POLYUNSATURATED FATTY-ACID, DOCOSAHEXAENOIC ACID, FOLIC-ACID, DOUBLE-BLIND, VITAMIN-E, MEDITERRANEAN DIET, NEURITE OUTGROWTH, SYNAPTIC PROTEINS

Abstract

Alzheimer's disease (AD) is a heterogeneous and devastating neurodegenerative disease with increasing socioeconomic burden for society. In the past 30 y, notwithstanding advances in the understanding of the pathogenesis of the disease and consequent development of therapeutic approaches to novel pathogenic targets, no cure has so far emerged.