Benzenin sıçan (rat rattus norvegigus-swiss albino) karaciğer ve böbrek dokusu adenozin deaminaz aktivitesi üzerine etkisi


Tezin Türü: Yüksek Lisans

Tezin Yürütüldüğü Kurum: Bursa Uludağ Üniversitesi, FEN-EDEBİYAT FAKÜLTESİ, BİYOLOJİ, Türkiye

Tezin Onay Tarihi: 2003

Tezin Dili: Türkçe

Öğrenci: ALİ TURHAN

Danışman: Egemen Dere

Özet:

In this study, 100 mg/kg dose of benzene which is used commonly in industry and known as a toxic and carcinogenic agent was administered to the Swiss albino Rat Rattus ttovegigus rats by intraperitonally injection and have been investigated on adenosine deaminase activity in the liver and kidney of rats after 0, 2, 4, 8, 16, 32 and 64 hours later. While Benzene formed significant inhibitions at the level of 0.05 probablity in the activity of liver Adenosine Deaminase after 16 and 32 hours, it did not formed any important activity or inhibition in the rest of time. It was not seen any variation in the activity of Adenosine Deaminase in Kidneys. On the other hand it was observed that the Adenosine Deaminase activity showed similar patterns with the serum physiologic Key words: Benzene, Adenosine Deaminase, Rat