Research Information System
Thesis Type: Doctorate
Institution Of The Thesis: Uludağ Üniversitesi, Turkey
Approval Date: 2007
Thesis Language: Turkish
Student: MURAT CENGİZ
Supervisor: HASAN HÜSEYİN ORUÇ
Open Archive Collection: AVESIS Open Access Collection
Abstract:Antibacterial drug pollution caused important problems can occur when manure is applied to agricultural lands. The aim of this study was therefore to determine the antibacterial drug pollution and effects of soil characteristics and seasonal changes on the fate of these drugs, and to evaluate the effects of antibacterial drug pollution in the environment. The soil samples were collected from agricultural lands fertilizing poultry (n=10), cattle (n=7) and poultry-cattle manure (n=4) in summer (total n=8) and autumn (total n=13). Solid phase extraction and HPLC system were used to detect the antibacterial drug concentrations in soil samples and standard methods were used to determine the soil characteristics. In summer, oxytetracycline was detected in four lands at concentrations of 19144μg/kg and 33μg/kg chlortetracycline was detected in one land. In autumn, oxytetracycline was detected in nine lands at concentrations of 4.97-104.69μg/kg and 72.83μg/kg chlortetracycline was detected in one land. Sulfonamides could not be detected in any land. Antibacterial drug pollution prevalence in autumn was higher than in summer. The highest concentration of antibacterial drugs in each season was detected in the lands fertilizing with poultry manure. In autumn, cation exchange capacity dropped while total N and P, organic carbon and Na concentrations enhanced when compared to the summer. It was detected that oxytetracycline concentration dropped while cation exchange capacity enhanced and the increasing of N, P, organic carbon and Na concentration caused to the detection at high concentrations of oxytetracycline in soil samples. Sulfonamid concentrations were dropped by enhancing of silt, organic carbon, K, Mg and Ni concentrations. In this study, tetracycline contamination was commonly detected in agricultural lands. The most important factor is cation exchange capacity in sorption of tetracyclines to the soil. Bacterial resistance could emerge and thus public and environmental health could be negatively affected by antibacterial drug pollution. However, it could not be expected that any toxic effect occurs on organisms.