Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence

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Sharifi-Rad J., Kobarfard F., Ata A., Ayatollahi S. A., Khosravi-Dehaghi N., Jugran A. K., ...Daha Fazla

BIOMOLECULES, cilt.9, sa.12, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 9 Sayı: 12
  • Basım Tarihi: 2019
  • Doi Numarası: 10.3390/biom9120777
  • Dergi Adı: BIOMOLECULES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Prosopis, vitexin, C-glycosyl flavones, food preservative, antiplasmodial, wound healing potential, INDIGENOUS MEDICINAL-PLANTS, LIQUID SMOKE, IN-VITRO, ANTIBACTERIAL ACTIVITY, ANTIOXIDANT CAPACITY, LEAF EXTRACT, JULIFLORA, CINERARIA, PODS, ALKALOIDS
  • Bursa Uludağ Üniversitesi Adresli: Hayır

Özet

Members of the Prosopis genus are native to America, Africa and Asia, and have long been used in traditional medicine. The Prosopis species most commonly used for medicinal purposes are P. africana, P. alba, P. cineraria, P. farcta, P. glandulosa, P. juliflora, P. nigra, P. ruscifolia and P. spicigera, which are highly effective in asthma, birth/postpartum pains, callouses, conjunctivitis, diabetes, diarrhea, expectorant, fever, flu, lactation, liver infection, malaria, otitis, pains, pediculosis, rheumatism, scabies, skin inflammations, spasm, stomach ache, bladder and pancreas stone removal. Flour, syrup, and beverages from Prosopis pods have also been potentially used for foods and food supplement formulation in many regions of the world. In addition, various in vitro and in vivo studies have revealed interesting antiplasmodial, antipyretic, anti-inflammatory, antimicrobial, anticancer, antidiabetic and wound healing effects. The phytochemical composition of Prosopis plants, namely their content of C-glycosyl flavones (such as schaftoside, isoschaftoside, vicenin II, vitexin and isovitexin) has been increasingly correlated with the observed biological effects. Thus, given the literature reports, Prosopis plants have positive impact on the human diet and general health. In this sense, the present review provides an in-depth overview of the literature data regarding Prosopis plants' chemical composition, pharmacological and food applications, covering from pre-clinical data to upcoming clinical studies.