ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.21, sa.6, ss.1284-1291, 2021 (SCI-Expanded)
Background: Inhibition of autophagy is reported to be a therapeutically effective strategy in overcoming resistance that is a deadly outcome in cancer. One of the most common reasons for chemo-resistance to treatment is the patients with tumors exhibiting a KRAS mutation, which occurs in approximately 40% of colorectal cancer patients.