ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.21, no.6, pp.1284-1291, 2021 (Journal Indexed in SCI)
Article / Article
Title of Journal :
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
Apoptosis, autophagy, metal-based compounds, ROS, colorectal cancer, chloroquine, PLATINUM(II) SACCHARINATE COMPLEXES, COLON-CANCER, CYTOTOXIC ACTIVITY, IN-VITRO, 5-FLUOROURACIL, CHLOROQUINE, CHEMOTHERAPY, BEVACIZUMAB, COMBINATION, ACTIVATION
Background: Inhibition of autophagy is reported to be a therapeutically effective strategy in overcoming resistance that is a deadly outcome in cancer. One of the most common reasons for chemo-resistance to treatment is the patients with tumors exhibiting a KRAS mutation, which occurs in approximately 40% of colorectal cancer patients.