Antimicrobial resistance and resistance genes in Flavobacterium psychrophilum isolates from Turkey

Satıcıoğlu İ. B., Duman M., Smith P., Wiklund T., Altun S.

AQUACULTURE, cilt.512, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 512
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.aquaculture.2019.734293
  • Dergi Adı: AQUACULTURE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Antimicrobial resistance genes, Flavobacterium psychrophilum, floR, NRI, sul2, TETRACYCLINE RESISTANCE, IN-VITRO, SUSCEPTIBILITY, BACTERIA, VALIDATION, MUTATIONS, PRIMERS, DISEASE, WATER
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

The antimicrobial susceptibilities of Turkish F. psychrophilum isolates were investigated using a Clinical and Laboratory Standards Institute (CLSI) standard microdilution testing protocol. The significance of the minimum inhibitory concentrations was determined by applying empirically and statistically determined epidemiological cut-off values calculated by normalized resistance analysis. Twenty-five F. psychrophilum isolates made over four years from three different trout species in five different regions were examined. All isolates were fully susceptible to amoxicillin and florfenicol, but 88% of our isolates were categorized as having reduced susceptibility to the two quinolones, oxolinic acid, and enrofloxacin. Eighty percent of the isolates were categorized as showing reduced susceptibility to oxytetracycline.