The LPA gene C93T polymorphism influences plasma lipoprotein(a) levels and is independently associated with susceptibility to peripheral arterial disease

Catalano, Mariella; Cortelazzo, Adriano; YILMAZ, YUSUF; Perilli, Edoardo; Carzaniga, Gianni; Emanuele, Enzo

doi:10.1016/j.cca.2007.09.014

The LPA gene C93T polymorphism influences plasma lipoprotein(a) levels and is independently associated with susceptibility to peripheral arterial disease

Catalano M., Cortelazzo A., YILMAZ Y., Perilli E., Carzaniga G., Emanuele E.

CLINICA CHIMICA ACTA, vol.387, pp.109-112, 2008 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 387
Publication Date: 2008
Doi Number: 10.1016/j.cca.2007.09.014
Journal Name: CLINICA CHIMICA ACTA
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.109-112
Bursa Uludag University Affiliated: No

Abstract

Background: Plasma lipoprotein(a) [Lp(a)] levels are mainly genetically determined. The C93T polymorphism is a naturally occurring variant of the LPA gene that may influence Lp(a) concentration. The role of Lp(a) in the pathogenesis of peripheral arterial disease (PAD) has not been firmly established.