The LPA gene C93T polymorphism influences plasma lipoprotein(a) levels and is independently associated with susceptibility to peripheral arterial disease


Catalano M., Cortelazzo A., YILMAZ Y., Perilli E., Carzaniga G., Emanuele E.

CLINICA CHIMICA ACTA, vol.387, pp.109-112, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 387
  • Publication Date: 2008
  • Doi Number: 10.1016/j.cca.2007.09.014
  • Journal Name: CLINICA CHIMICA ACTA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.109-112
  • Bursa Uludag University Affiliated: No

Abstract

Background: Plasma lipoprotein(a) [Lp(a)] levels are mainly genetically determined. The C93T polymorphism is a naturally occurring variant of the LPA gene that may influence Lp(a) concentration. The role of Lp(a) in the pathogenesis of peripheral arterial disease (PAD) has not been firmly established.