The LPA gene C93T polymorphism influences plasma lipoprotein(a) levels and is independently associated with susceptibility to peripheral arterial disease

Catalano M., Cortelazzo A., YILMAZ Y., Perilli E., Carzaniga G., Emanuele E.

CLINICA CHIMICA ACTA, cilt.387, ss.109-112, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 387
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.cca.2007.09.014
  • Dergi Adı: CLINICA CHIMICA ACTA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.109-112
  • Bursa Uludağ Üniversitesi Adresli: Hayır

Özet

Background: Plasma lipoprotein(a) [Lp(a)] levels are mainly genetically determined. The C93T polymorphism is a naturally occurring variant of the LPA gene that may influence Lp(a) concentration. The role of Lp(a) in the pathogenesis of peripheral arterial disease (PAD) has not been firmly established.