Prevention of Epidural Fibrosis in Rats by Local or Systemic Administration of Citicoline

Savran M., BEKAR A., CANSEV M., Tolunay S., ULUS İ. H., TAŞKAPILIOĞLU M. Ö.

TURKISH NEUROSURGERY, vol.22, no.5, pp.634-640, 2012 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 5
  • Publication Date: 2012
  • Doi Number: 10.5137/1019-5149.jtn.6008-12.0
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.634-640
  • Keywords: Epidural fibrosis, Annular fenestration, Laminatomy, Citicoline, Rat, BACK SURGERY SYNDROME, AUTONOMIC NERVOUS-SYSTEM, CDP-CHOLINE, PERIDURAL FIBROSIS, LUMBAR DISKECTOMY, FUNCTIONAL RECOVERY, CEREBRAL-ISCHEMIA, LAMINECTOMY MODEL, SCAR FORMATION, ADCON-L
  • Bursa Uludag University Affiliated: Yes

Abstract

AIM: The objective of this study was to investigate the effect of citicoline administration on epidural fibrosis which is a frequent complication of lumbar disc surgery with no effective treatment or preventive surgical technique.