Successful Treatment of Central Nervous System Involvement in Posttransplant EBV-related Lymphoproliferative Disease With Intrathecal Rituximab Therapy.

Aslan F., Güler S., Sezgin Evim M., Aslier M., Yazici Z., Öztürk Nazlioğlu H., ...Daha Fazla

Journal of pediatric hematology/oncology, cilt.45, sa.5, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 5
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1097/mph.0000000000002592
  • Dergi Adı: Journal of pediatric hematology/oncology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, MEDLINE
  • Anahtar Kelimeler: CNS involvement, PTLD, HSCT, intrathecal rituximab, STEM-CELL TRANSPLANTATION, CNS
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

The posttransplant lymphoproliferative disease is a severe cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation. Central Nervous System involvement in EBV-related PTLD is rare, and there is no standard treatment recommendation. We present our patient and discuss other previously reported cases of EBV-associated PTLD with CNS involvement.