Duckweed (Lemna minor L.) has a wide application in Turkey having suitable climatic conditions. In this study, the growth of duckweed was assessed in laboratory scale experiments, They were fed with municipal and industrial wastewater at constant temperature. COD, total nitrogen (TN), total phosphorus (TP) and ortho-phosphate (OP) removal efficiencies of the reactors were monitored by sampling influent and effluent of the system. Removal efficiency in this study reflects optimal results: 73-84% COD removal, 83-87% TN removal, 70-85% TP removal and 83-95% OP removal. The results show that the duckweed-based wastewater treatment is capable of treating the laboratory wastewater.