The first examples of di- and cis triaryl-3a,4,5,6-tetrahydroimidazo[1,5-b]isoxazoles and their ring-opening reactions

Coskun N. , Tat F., Guven O., Ulku D., Arici C.

TETRAHEDRON LETTERS, vol.41, no.28, pp.5407-5409, 2000 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 28
  • Publication Date: 2000
  • Doi Number: 10.1016/s0040-4039(00)00864-9
  • Title of Journal : TETRAHEDRON LETTERS
  • Page Numbers: pp.5407-5409


The Delta(3)-imidazoline 3-oxides 1 undergo diastereoselective cycloaddition with dimethyl acetylenedicarboxylate 2 to give 3a,4,5,6-tetrahydroimidazo[1,5-b]isoxazoles 3. Thermal and base induced ring-opening reactions of compounds 3 were demonstrated. (C) 2000 Elsevier Science Ltd. All rights reserved.