Meckel Gruber syndrome, A case report.

Aslan K., Aslan E. K., ORHAN A., Atalay M. A.

Organogenesis, vol.11, no.2, pp.87-92, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1080/15476278.2015.1055431
  • Journal Name: Organogenesis
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.87-92
  • Bursa Uludag University Affiliated: Yes

Abstract

Introduction: Meckel-Gruber Syndrome was first described by J R Meckel in 1822. It is an autosomal recessive disorder, and is caused by the failure of mesodermal induction. The typical triad of Meckel-Gruber Syndrome (MGS) involves meningo-encephalocele, polycystic kidneys and postaxial polydactyly. The worldwide incidence varies from 1 in 1.300 to 1 in 140.000 live births.