MOLECULAR CANCER, vol.11, 2012 (Journal Indexed in SCI)
Article / Article
Title of Journal :
Mitochondria, Glycolysis, Tricarboxylic acid cycle, Electron transport chain, Oncogene, MITOCHONDRIAL METABOLISM, PROSTATE-CANCER, SUBUNITS, OXYGEN, CELLS, TRANSFORMATION, EXPRESSION, INCREASES, ONCOGENE, PROTEOME
Background: Constitutive activation of Ras in immortalized bronchial epithelial cells increases electron transport chain activity, oxygen consumption and tricarboxylic acid cycling through unknown mechanisms. We hypothesized that members of the Ras family may stimulate respiration by enhancing the expression of the Vb regulatory subunit of cytochrome c oxidase (COX).