Distribution of RET Mutations and Evaluation of Treatment Approaches in Hereditary Medullary Thyroid Carcinoma in Turkey

Aydogan, Berna; Yuksel, Bagdagul; Tuna, Mazhar; Basaran, Mehtap; Kocaeli, Aysen; Ertorer, Melek; Aydin, Kadriye; GÜLDİKEN, SİBEL; ŞİMŞEK, Yasin; Karaca, Zuleyha; Yilmaz, Merve; Akturk, Mujde; Anaforoglu, Inan; Kebapci, Nur; Duran, Cevdet; Taslipinar, Abdullah; KULAKSIZOĞLU, MUSTAFA; Gursoy, Alptekin; DAĞDELEN, SELÇUK; Erdogan, Murat

doi:10.4274/jcrpe.2219

Distribution of RET Mutations and Evaluation of Treatment Approaches in Hereditary Medullary Thyroid Carcinoma in Turkey

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Aydogan B. I., Yuksel B., Tuna M. M., Basaran M. N., Kocaeli A. A., Ertorer M. E., ...More

JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY, vol.8, no.1, pp.13-20, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 8 Issue: 1
Publication Date: 2016
Doi Number: 10.4274/jcrpe.2219
Journal Name: JOURNAL OF CLINICAL RESEARCH IN PEDIATRIC ENDOCRINOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Page Numbers: pp.13-20
Bursa Uludag University Affiliated: Yes

Abstract

Objective: This retrospective multicenter study, centrally conducted and supported by the Society of Endocrinology and Metabolism of Turkey, aimed to evaluate the impact of free RET proto-oncogene testing in medullary thyroid carcinoma (MTC) patients. Surgical timing, adequacy of the treatment, and frequency of prophylactic thyroidectomy (PTx) in mutation carriers were also assessed.