J Biotechnol Biomater , cilt.7, sa.1, ss.83, 2017 (Hakemli Dergi)
Fruits contain phenolic additives which may show more or less antimicrobial effects. Depending on their antioxidant properties
phenolic substances, which have effect mostly on color, flavor and durability of fruits and vegetables, are closely related with
human health in terms of antimicrobial, anti-carcinogenic and anti-mutagenic activities. In the long term, bacterial resistance
against antimicrobial agents may cause problems in fighting against several diseases. Therefore investigation of novel antimicrobial
agents derived from new and natural sources have become important. In this study, seeds of some fruits (Prunus persica, Prunus
cerasus, Prunus avium and Prunus armeniaca) were investigated against some clinically substantial pathogenic bacteria (Salmonella
typhimurium ATCC 14028, Klebsiella pneumoniae ATCC 700603, E. coli ATCC 25922, E. coli ATCC 35218, Staphylococcus aureus ATCC
25923, Yersinia enterocolitica ATCC 9610 ve Enterococcus faecalis ATCC 29212) by using well diffusion method. For this purpose, seeds
from fruits were crushed into small pieces and, were extracted by Soxhlet using methanol as solvent. After incubation, the highest
zone diameter (15 mm) was obtained against E. faecalis in the sample of P. cerasus seed, and also against S. aureus in the sample of P.
armeniaca seed (14 mm). Hence, this shows that the products can be potential new antimicrobial agents pharmacologically