Investigation of the level of response to botulinum-a toxin injection treatment in patient with lower urinary system disfonction Alt üriner system disfonksiyonu olan olgularda botulinum-a toksini enjeksiyonu tedavisine yanıt düzeyinin araştırılması

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SAĞLAM S., Sezer B. T., YILMAZ M. U., KILIÇ N., BALKAN M. E.

Cocuk Cerrahisi Dergisi, vol.37, no.1, pp.28-35, 2023 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 1
  • Publication Date: 2023
  • Doi Number: 10.29228/jtaps.58154
  • Journal Name: Cocuk Cerrahisi Dergisi
  • Journal Indexes: Scopus
  • Page Numbers: pp.28-35
  • Keywords: bladder elastography, Botulinum Toxin-A injection, Lower urinary system dysfunction
  • Bursa Uludag University Affiliated: Yes

Abstract

Objective: In our study, we aimed to examine the response level to treatment with different diagnostic methods in selected patients who were treated bladder with Botulinum Toxin-A (BTA) injection due to lower urinary system dysfunction. Method: In this prospective study; injected cases in pre-op and post-op period; urodynamic study was subjected to various diagnostic methods such as Voiding Disorder Symptom Scoring (VDSS) and Bladder Elastography (ME). In addition, a control group consisting of urologically healthy patients was formed for ME. Results: Significant changes were found in functional bladder capacity and bladder compliance values and VDSS values in the pre-op and post-op urodynamic studies of the patients who received BTA injection. Similar changes were not reflected in ME parameters. Conclusion: BTA injection into the bladder in cases diagnosed with lower urinary system dysfunction; It is an effective treatment method. Although this efficacy can be demonstrated by urodynamic studies and various symptom scorings, further standardization studies are needed for ME.