SEASONAL-VARIATION OF PROSTATIC ACID PHOSPHATE AND PROSTATE-SPECIFIC ANTIGEN IN PATIENTS WITHOUT PROSTATIC MALIGNANCY

SIMSEK U., KUTLU S., YAVASCAOUGLU I., OKTAY B., OZYURT M.

EUROPEAN UROLOGY, vol.21, pp.111-114, 1992 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21
  • Publication Date: 1992
  • Doi Number: 10.1159/000474906
  • Journal Name: EUROPEAN UROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.111-114
  • Bursa Uludag University Affiliated: No

Abstract

The seasonal pattern of prostatic acid phosphatase (PAP) and prostate specific antigen (PSA) in nonmalignant males was investigated. Serum levels were measured in 1,540 men during a 3-year period with radioimmunoassay methods using monoclonal antibody techniques. All of the tested individuals were free of prostatic malignancy. During each of the 3 years, PAP ans PSA showed a rise, especially in spring. The mean PSA level in spring showed a statistically important difference when compared with winter, fall and summer mean levels (p < 0.05). However, no significant difference of PAP levels was estimated seasonally in the 3 years, which shows that an important marker of prostatic cancer can va with seasons.