THE EFFECTS OF HUMAN AMNIOTIC MEMBRANE AND PERIOSTEAL AUTOGRAFT ON TENDON HEALING: EXPERIMENTAL STUDY IN RABBITS

Ozboluk S., Ozkan Y., Ozturk A., Gul N. Y., Ozdemir R. M., Yanik K.

JOURNAL OF HAND SURGERY-EUROPEAN VOLUME, sa.4, ss.262-268, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: Sayı: 4
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1177/1753193409337961
  • Dergi Adı: JOURNAL OF HAND SURGERY-EUROPEAN VOLUME
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.262-268
  • Anahtar Kelimeler: flexor tendon injury, adhesion formation, periost, human amniotic membrane, experiment, EARLY ACTIVE MOBILIZATION, FLEXOR TENDON, PERITENDINOUS ADHESIONS, HYALURONIC-ACID, RESTRICTIVE ADHESIONS, REPAIR, SHEATH, INJURY, MOTION, MODEL
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

In this study, the effects of periosteal autograft and human amniotic membrane on tendon healing were compared. Forty-two New Zealand rabbits were divided into three groups. Flexor digitorum fibularis tendons were cut and repaired with a modified Kessler technique and circumferential sutures in all groups. Tendon repair alone was carried out in group 1, tendon repair and application of human amniotic membrane was done in group 2 and tendon repair and application of periosteal autograft was done in group 3. Biomechanical and histopathological examinations were done 2 and 6 weeks postoperatively. Biomechanical examination showed that group 3 was the strongest at weeks 2 and 6. Adhesion, inflammation and new bone formation showed no difference between groups at week 2. However, adhesion formation was found to be less in groups 2 and 3 than group 1 at week 6. The application of periosteal autograft might be useful in repair of tendon injuries.