Akademik Veri Yönetim Sistemi
Current Research in Dental Sciences, cilt.32, sa.4, ss.290-296, 2022 (Scopus)
The aim of periodontal therapy is to eliminate inflammation, stop tissue destruction, regain the bone support and soft tissue lost and maintain or restore the stability of the remaining teeth. There are many difficulties in obtaining the desired level of morphological and physiological regeneration in periodontal tissues lost with conventional periodontal therapy. Stem cells are promising as endogenous cell sources for regenerative therapy in medicine and dentistry, with their ability to differentiate into multiple cell types that built hard and soft tissues and to self-renewable. For this reason, research on stem cell applications, which are believed to directly guide the wound healing processes of periodontal tissues, is increasing day by day. In this review, the diagnostic criteria and classification of stem cells are summarized by reviewing the current lit-erature. An overview of clinical and experimental studies is presented on dental pulpal stem cells, periodontal ligament stem cells, gingival mesenchymal stem cells, exfoliated deciduous teeth stem cells, dental follicle stem cells, bone marrow mesenchymal stem cells, adipose tissue stem cells, umbilical cord stem cells. Research into the use of stem cells for tissue regeneration has the potential to significantly influence future periodontal treatment strategies.