Copy For Citation
Bagdas D., GÜRÜN M. S., Flood P., Papke R. L., Damaj M. I.
CURRENT NEUROPHARMACOLOGY, vol.16, no.4, pp.415-425, 2018 (SCI-Expanded)
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Publication Type:
Article / Review
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Volume:
16
Issue:
4
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Publication Date:
2018
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Doi Number:
10.2174/1570159x15666170818102108
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Journal Name:
CURRENT NEUROPHARMACOLOGY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.415-425
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Keywords:
alpha 7 nicotinic acetylcholine receptors, nicotine, pain, inflammation, modulators, anti-inflammatory, agonists, POSITIVE ALLOSTERIC MODULATOR, CHOLINERGIC ANTIINFLAMMATORY PATHWAY, GATED ION-CHANNEL, X-RAY-STRUCTURE, NEUROPATHIC PAIN, ANIMAL-MODELS, SPINAL-CORD, BINDING-SITES, HUMAN MONOCYTES, DRUG DISCOVERY
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Bursa Uludag University Affiliated:
Yes
Abstract
Background: Nicotine and nicotinic acetylcholine receptors (nAChRs) have been explored for the past three decades as targets for pain control. The aim of this review is to introduce readers particularly to alpha 7 nAChRs in a perspective of pain and its modulation.