Octreotide ameliorates dermal fibrosis in bleomycin-induced scleroderma

Oyucu Orhan, SİBEL; Tektemur, Ahmet; Gozel, Nevzat; Ozercan, Ibrahim; Yolbas, Servet; Yildirim, Ahmet; Onalan, Ebru; Koca, Suleyman

doi:10.3906/sag-1707-88

Octreotide ameliorates dermal fibrosis in bleomycin-induced scleroderma

Oyucu Orhan S., Tektemur A., Gozel N., Ozercan I. H., Yolbas S., Yildirim A., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.48, sa.4, ss.886-891, 2018 (SCI-Expanded, Scopus, TRDizin)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 48 Sayı: 4
Basım Tarihi: 2018
Doi Numarası: 10.3906/sag-1707-88
Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.886-891
Bursa Uludağ Üniversitesi Adresli: Hayır

Özet

Background/aim: Insulin-like growth factor (IGF)-I is a differentiation and growth factor. Antifibrotic action of octreotide has been reported in pulmonary fibrosis. The present study aimed to research the prophylactic and therapeutic potential of octreotide on a bleomycin (BLM)-induced experimental scleroderma model.