Octreotide ameliorates dermal fibrosis in bleomycin-induced scleroderma
TURKISH JOURNAL OF MEDICAL SCIENCES, vol.48, no.4, pp.886-891, 2018 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 48 Issue: 4
- Publication Date: 2018
- Doi Number: 10.3906/sag-1707-88
- Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.886-891
- Bursa Uludag University Affiliated: No
Abstract
Background/aim: Insulin-like growth factor (IGF)-I is a differentiation and growth factor. Antifibrotic action of octreotide has been reported in pulmonary fibrosis. The present study aimed to research the prophylactic and therapeutic potential of octreotide on a bleomycin (BLM)-induced experimental scleroderma model.