Decreased nitric oxide production in primary open-angle glaucoma

Doganay S., EVEREKLİOĞLU C., Turkoz Y., Er H.

EUROPEAN JOURNAL OF OPHTHALMOLOGY, vol.12, no.1, pp.44-48, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 1
  • Publication Date: 2002
  • Doi Number: 10.1177/112067210201200109
  • Journal Name: EUROPEAN JOURNAL OF OPHTHALMOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.44-48
  • Bursa Uludag University Affiliated: No

Abstract

PURPOSE. Raised intraocular pressure (IOP) is the major risk factor responsible for optic nerve damage in primary open-angle glaucoma (POAG). The trabecular meshwork acts as a valve in aqueous outflow and relaxes with nitric oxide (NO) agonists. Since NO is synthesized by endothelium and smooth muscle elsewhere in the body, this study investigated the NO levels in the aqueous humor of patients with POAG compared with cataract patients.