The reconstruction precision of gaseous detectors is limited by losses of primary electrons during signal formation. In addition to common gas related losses, like attachment, Micromegas suffer from electron absorption during its transition through the micro mesh. This study aims for a deepened understanding of electron losses and their dependency on the mesh geometry. It combines experimental results obtained with a novel designed Exchangeable Mesh Micromegas (ExMe) and advanced microscopic tracking simulations (ANSYS and Garfield+ +) of electron drift and mesh transition. (C) 2015 Elsevier B.V. All rights reserved.