Efficient and chemoselective alkyl bromoacetate-Zn mediated transesterification method

Coskun N. , Er M.

TETRAHEDRON, vol.59, no.19, pp.3481-3485, 2003 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 19
  • Publication Date: 2003
  • Doi Number: 10.1016/s0040-4020(03)00472-1
  • Title of Journal : TETRAHEDRON
  • Page Numbers: pp.3481-3485


Alkyl bromoacetates were shown to be versatile transesterification reagents. Isoxazoles underwent chemoselective transesterification when treated with alkyl bromoacetate-Zn in THF at reflux. A suggested mechanism of the new reaction was discussed. (C) 2003 Elsevier Science Ltd. All rights reserved.