Investigation of TNF-alpha gene (G308A) and GSTP1 gene (Ile105Val) polymorphisms in Turkish patients with retinopathy of prematurity

Ture M., YILDIZ M., Karkucak M., Gulten E. T., SIĞIRLI D., ÖZMEN A. T., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, sa.1, ss.164-169, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3906/sag-1307-94
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.164-169
  • Anahtar Kelimeler: TNF-alpha, GSTP1, gene polymorphism, retinopathy of prematurity, TUMOR-NECROSIS-FACTOR, NORRIE-DISEASE GENE, ENDOTHELIAL GROWTH-FACTOR, BIRTH-WEIGHT INFANTS, PROMOTER REGION, DIABETIC-RETINOPATHY, MISSENSE MUTATIONS, ASSOCIATION, SUSCEPTIBILITY, POPULATION
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background/aim: Retinopathy of prematurity (ROP) is one of the most frequent causes of blindness in newborn babies. Currently, its etiology is not fully understood. In this study we aimed to investigate the correlation between a patient group with ROP and a control group in terms of the tumor necrosis factor- alpha (TNF-alpha) (G308A) gene and glutathione-S-transferase P1 (GSTP1) (Ile105Val) gene polymorphism.