High-content cytometry and transcriptomic biomarker profiling of human B-cell activation

Hennig, Christian; Ilginus, Claudia; Boztug, Kaan; Skokowa, Julia; Marodi, Laszlo; Szaflarska, Anna; Sass, Mareike; Pignata, Claudio; Kilic, SARA; Caragol, Isabel; Baumann, Ulrich; Klein, Christoph; Welte, Karl; Hansen, Gesine

doi:10.1016/j.jaci.2013.06.047

High-content cytometry and transcriptomic biomarker profiling of human B-cell activation

Hennig C., Ilginus C., Boztug K., Skokowa J., Marodi L., Szaflarska A., ...Daha Fazla

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, cilt.133, sa.1, ss.172-190, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 133 Sayı: 1
Basım Tarihi: 2014
Doi Numarası: 10.1016/j.jaci.2013.06.047
Dergi Adı: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.172-190
Anahtar Kelimeler: Primary immunodeficiency, primary antibody deficiency, B-cell immunology, chip cytometry, AUTOSOMAL RECESSIVE FORM, ATAXIA-TELANGIECTASIA, DEFICIENCY, IMMUNODEFICIENCIES, EXPRESSION, MUTATIONS, PATHWAY, AID, ATM
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background: Primary antibody deficiencies represent the most prevalent, although very heterogeneous, group of inborn immunodeficiencies, with a puzzling complexity of cellular and molecular processes involved in disease pathogenesis.