Creutzfeldt-Jakob Disease: Report of Four Cases and Review of the Literature


Ozatalay F., TOLUNAY Ş. , Ozgun G., BEKAR A. , ZARİFOĞLU M.

TURKISH JOURNAL OF PATHOLOGY, vol.31, no.2, pp.148-152, 2015 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.5146/tjpath.2013.01195
  • Title of Journal : TURKISH JOURNAL OF PATHOLOGY
  • Page Numbers: pp.148-152

Abstract

Creutzfeldt-Jakob disease is a very rare, progressive neurodegenerative disorder that is incurable and always fatal. It is one of the transmissible spongiform encephalopathies caused by prions. Multiple vacuoles in neuropil and neuronal loss in the gray matter gives the classical sponge-like appearance of brain and are responsible for the typical clinical symptoms.