Inhibitory Effect of Sub-conjunctival Tocilizumab on Alkali Burn Induced Corneal Neovascularization in Rats

Sari E., Yazici A., Aksit H., Yay A., Sahin G., Yildiz O., ...More

CURRENT EYE RESEARCH, vol.40, no.1, pp.48-55, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.3109/02713683.2014.914541
  • Journal Name: CURRENT EYE RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.48-55
  • Keywords: Alkali burn induced corneal neovascularization, Interleukin-6 receptor antibody, rat, tocilizumab, ANGIOGENESIS, BEVACIZUMAB, INTERLEUKIN-6, MODEL, EXPRESSION, RECEPTORS, ANTIBODY, DISEASES, THERAPY, UVEITIS
  • Bursa Uludag University Affiliated: No

Abstract

Background: To evaluate the effects of sub-conjunctivally applied interleukin-6 receptor (IL-6R) antibody (tocilizumab) on alkali burn induced corneal neovascularization (CNV) in rats.