ARKIVOC, vol.2022, no.9, pp.158-167, 2022 (SCI-Expanded)
A series of anthraquinone derivatives (1-11) was prepared using alkyl halides, quinizarin, and danthron. The
structural analysis of new compounds was carried out by 1H, 13C NMR, IR, and UV-Vis spectroscopic
techniques. Xanthine oxidase inhibitory activities of compounds were measured using allopurinol as a
standard. Inhibition abilities were identified by measuring the uric acid formation at 294 nm at 37 °C.
According to the IC50 values of the compounds, it was observed that all the compounds in the group had
higher inhibition values than allopurinol.