Effect of different doses of 2aEuroaminoethoxydiphenyl borate on intestinal ischemia-reperfusion injury

Basbug, Murat; Yildar, Murat; Yaman, Ismail; Cavdar, Faruk; ÖZKAN, ÖMER; AKŞİT, HASAN; ÖZYİĞİT, MUSA; ASLAN, FİGEN; Derici, Hayrullah

doi:10.1007/s10353-016-0452-y

Effect of different doses of 2aEuroaminoethoxydiphenyl borate on intestinal ischemia-reperfusion injury

Copy For Citation

Basbug M., Yildar M., Yaman I., Cavdar F., ÖZKAN Ö. F., AKŞİT H., ...More

EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA, vol.49, no.1, pp.32-37, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 49 Issue: 1
Publication Date: 2017
Doi Number: 10.1007/s10353-016-0452-y
Journal Name: EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.32-37
Keywords: Intestinal ischemia, 2-APB, Ischemia-reperfusion injury, MESENTERIC ISCHEMIA/REPERFUSION INJURY, REMOTE ORGANS, FREE-RADICALS, RATS, MECHANISMS
Bursa Uludag University Affiliated: Yes

Abstract

Background Acute mesenteric ischemia is a life-threatening clinical entity. 2-Aminoethoxydiphenyl borate (2-APB) is a membrane-permeable modulator of intracellular inositol triphosphate-induced calcium release. We investigated the effects of different 2-APB doses on intestinal ischemia-reperfusion injury in an experimental rat model.