Effect of different doses of 2aEuroaminoethoxydiphenyl borate on intestinal ischemia-reperfusion injury
EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA, cilt.49, sa.1, ss.32-37, 2017 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 49 Sayı: 1
- Basım Tarihi: 2017
- Doi Numarası: 10.1007/s10353-016-0452-y
- Dergi Adı: EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.32-37
- Anahtar Kelimeler: Intestinal ischemia, 2-APB, Ischemia-reperfusion injury, MESENTERIC ISCHEMIA/REPERFUSION INJURY, REMOTE ORGANS, FREE-RADICALS, RATS, MECHANISMS
- Bursa Uludağ Üniversitesi Adresli: Evet
Özet
Background Acute mesenteric ischemia is a life-threatening clinical entity. 2-Aminoethoxydiphenyl borate (2-APB) is a membrane-permeable modulator of intracellular inositol triphosphate-induced calcium release. We investigated the effects of different 2-APB doses on intestinal ischemia-reperfusion injury in an experimental rat model.