Effect of different doses of 2aEuroaminoethoxydiphenyl borate on intestinal ischemia-reperfusion injury

Basbug M., Yildar M., Yaman I., Cavdar F., ÖZKAN Ö. F., AKŞİT H., ...Daha Fazla

EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA, cilt.49, sa.1, ss.32-37, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s10353-016-0452-y
  • Dergi Adı: EUROPEAN SURGERY-ACTA CHIRURGICA AUSTRIACA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.32-37
  • Anahtar Kelimeler: Intestinal ischemia, 2-APB, Ischemia-reperfusion injury, MESENTERIC ISCHEMIA/REPERFUSION INJURY, REMOTE ORGANS, FREE-RADICALS, RATS, MECHANISMS
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background Acute mesenteric ischemia is a life-threatening clinical entity. 2-Aminoethoxydiphenyl borate (2-APB) is a membrane-permeable modulator of intracellular inositol triphosphate-induced calcium release. We investigated the effects of different 2-APB doses on intestinal ischemia-reperfusion injury in an experimental rat model.