Moderate hypothermia prevents brain stem oxidative stress injury after hemorrhagic shock


Guven H., Amanvermez R., Malazgirt Z., Kaya E., Doganay Z., Celik C., ...More

JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE, vol.53, no.1, pp.66-72, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 1
  • Publication Date: 2002
  • Doi Number: 10.1097/00005373-200207000-00014
  • Journal Name: JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.66-72
  • Keywords: hemorrhagic shock, hemorrhage, hypothermia, brain stem injury, CEREBRAL-BLOOD-FLOW, NITRIC-OXIDE, OXYGEN-CONSUMPTION, TRAUMA-HEMORRHAGE, POTENTIAL ROLE, TEMPERATURE, SURVIVAL, SLICES, MILD, HIPPOCAMPUS
  • Bursa Uludag University Affiliated: Yes

Abstract

Background: The purpose of this study was to investigate the effects of temperature on oxidative stress in brain stem tissue induced by hemorrhagic shock. We researched the hemorrhagic oxidative stress at various core temperatures using reduced glutathione (GSH) levels and thiobarbituric acid-reactive substances (TBARS) as markers of lipid peroxidation in brain stem homogenate.