Effects of intracerebroventricularly injected glucagon-like peptide-1 on cardiovascular parameters; role of central cholinergic system and vasopressin


Isbil-Buyukcoskun N., Gulec G.

REGULATORY PEPTIDES, vol.118, pp.33-38, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 118
  • Publication Date: 2004
  • Doi Number: 10.1016/j.regpep.2003.10.025
  • Journal Name: REGULATORY PEPTIDES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.33-38
  • Keywords: blood pressure, heart rate, mecamylamine, atropine, V-1 receptor antagonist, rat, ARTERIAL-BLOOD PRESSURE, GENE-EXPRESSION, MESSENGER-RNAS, HEART-RATE, RAT-BRAIN, RECEPTOR, AMIDE, EXENDIN-4, GLP-1, SECRETION
  • Bursa Uludag University Affiliated: Yes

Abstract

We aimed to investigate the effects of intracerebroventricularly (i.c.v.) injected glucagon-like peptide-1 (GLP-1) on blood pressure and heart rate, and whether central cholinergic system and vasopressinergic system play roles in these effects.