The Frailty of Advanced Kidney Disease: The Role of Mitochondria

YILDIZ A., Ikizler T. A.

TURKISH JOURNAL OF NEPHROLOGY, cilt.31, sa.3, ss.190-193, 2022 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 31 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5152/turkjnephrol.2022.22317
  • Dergi Adı: TURKISH JOURNAL OF NEPHROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.190-193
  • Anahtar Kelimeler: Chronic kidney disease, mitochondria, muscles
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Uremic toxins contribute to the impairment of mitochondrial function that subsequently could result in organ failure. Mitochondrial dysfunction also plays an essential role in the pathogenesis of sarcopenia in chronic kidney disease patients. It may be feasible to assess the effect of mitochondrial-targeted drugs to treat sarcopenia in patients with chronic kidney disease.