The Effects of Reboxetine and Venlafaxine on ECG Variables in Depressed Patients

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EKER S. S., AKKAYA C., Cangur S., Yuvanc U., SARANDÖL A., KIRLI S.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, vol.21, no.1, pp.11-17, 2011 (SCI-Expanded, Scopus, TRDizin)

• Publication Type: Article / Article
• Volume: 21 Issue: 1
• Publication Date: 2011
• Doi Number: 10.5350/kpb-bcp201121103
• Journal Name: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Page Numbers: pp.11-17
• Bursa Uludag University Affiliated: Yes

Abstract

Objective: Antidepressants exert distinct effects on cardiac autonomic nervous system function depending on their receptor profile; thus, different groups of antidepressants are expected to influence cardiac parameters in varying degrees. This study compares the effects of venlafaxine, a serotonin and noradrenaline reuptake inhibitor and reboxetine, a selective noradrenaline reuptake inhibitor, on ECG parameters and vital signs.