The Effects of Reboxetine and Venlafaxine on ECG Variables in Depressed Patients

EKER S. S., AKKAYA C., Cangur S., Yuvanc U., SARANDÖL A., KIRLI S.

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, vol.21, no.1, pp.11-17, 2011 (SCI-Expanded) identifier identifier


Objective: Antidepressants exert distinct effects on cardiac autonomic nervous system function depending on their receptor profile; thus, different groups of antidepressants are expected to influence cardiac parameters in varying degrees. This study compares the effects of venlafaxine, a serotonin and noradrenaline reuptake inhibitor and reboxetine, a selective noradrenaline reuptake inhibitor, on ECG parameters and vital signs.