Serum levels of endocan, claudin-5 and cytokines in migraine


Yucel M., Kotan D., Ciftci G. G. , Ciftci I. H. , Cikriklar H. İ.

EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.20, no.5, pp.930-936, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 5
  • Publication Date: 2016
  • Title of Journal : EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
  • Page Numbers: pp.930-936

Abstract

OBJECTIVE: Endothelial dysfunction is involved in inflammatory disorders, migration, angiogenesis, and tumor progression. There is a known relationship between migraine and inflammation; however, there are conflicting data as to whether there is a link between migraine and endothelial dysfunction. The current study aimed to determine the relationships between migraine and levels of serum Endocan (ESM-1), Claudin-5 (CLDN5), IL-1 beta, IL-6 and TNF-alpha levels, which are proven indicators of endothelial dysfunction and inflammation in patients with migraine.