Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency.

Kıykım, Ayça; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Çekiç, ŞÜKRÜ; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Kilic, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Agrebi, Nourhen; Kara, Manolya; Özen, Ahmet; Somer, SARA; Özen, Ahmet; Aktay Ayaz, Nuray; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Kilic Ss, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Özen, Ahmet; Barış, Safa

doi:10.1016/j.jaip.2019.06.011

Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency.

Atıf İçin Kopyala

Kıykım A., Özen A. O., Özen A. O., Özen A. O., Özen A. O., Çekiç Ş., ...Daha Fazla

The journal of allergy and clinical immunology. In practice, cilt.7, sa.8, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 7 Sayı: 8
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.jaip.2019.06.011
Dergi Adı: The journal of allergy and clinical immunology. In practice
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: LPS-responsive beige-like anchor, Immune dysregulation, Abatacept, T follicular helper cells, Autoimmunity, IMMUNE DYSREGULATION, CTLA-4 CHECKPOINT, MUTATIONS, POLYENDOCRINOPATHY, ENTEROPATHY, DISEASE
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

BACKGROUND: LPS-responsive beige-like anchor (LRBA) deficiency presents with susceptibility to infections, autoimmunity, and lymphoproliferation. The long-term efficacy of cytotoxic T-lymphocyte-associated antigen 4-immunoglobulin (abatacept) as targeted therapy for its immune dysregulatory features remains to be established.