Autoantibodies against type I IFNs in patients with critical influenza pneumonia.

Zhang, Qian; Pizzorno, Andrés; Miorin, Lisa; Bastard, Paul; Gervais, Adrian; Le Voyer, Tom; Bizien, Lucy; Manry, Jeremy; Rosain, Jérémie; Philippot, Quentin; Goavec, Kelian; Padey, Blandine; Cupic, Anastasija; Laurent, Emilie; Saker, Kahina; Vanker, Martti; Särekannu, Karita; García-Salum, Tamara; Ferres, Marcela; Le Corre, Nicole; Sánchez-Céspedes, Javier; Balsera-Manzanero, María; Carratala, Jordi; Retamar-Gentil, Pilar; Abelenda-Alonso, Gabriela; Valiente, Adoración; Tiberghien, Pierre; Zins, Marie; Debette, Stéphanie; Meyts, Isabelle; Haerynck, Filomeen; Castagnoli, Riccardo; Notarangelo, Luigi; Gonzalez-Granado, Luis; Dominguez-Pinilla, Nerea; Andreakos, Evangelos; Triantafyllia, Vasiliki; Rodríguez-Gallego, Carlos; Solé-Violán, Jordi; Ruiz-Hernandez, José; Rodríguez de Castro, Felipe; Ferreres, José; Briones, Marisa; Wauters, Joost; Vanderbeke, Lore; Feys, Simon; Kuo, Chen-Yen; Lei, Wei-Te; Ku, Cheng-Lung; Tal, Galit; Etzioni, Amos; Hanna, Suhair; Fournet, Thomas; Casalegno, Jean-Sebastien; Queromes, Gregory; Argaud, Laurent; Javouhey, Etienne; Rosa-Calatrava, Manuel; Cordero, Elisa; Aydillo, Teresa; Medina, Rafael; Kisand, Kai; Puel, Anne; Jouanguy, Emmanuelle; Abel, Laurent; Cobat, Aurélie; Trouillet-Assant, Sophie; García-Sastre, Adolfo; Casanova, Jean-Laurent; Abel, Laurent; Aiuti, Alessandro; Al-Muhsen, Saleh; Al-Mulla, Fahd; Anderson, Mark; Andreakos, Evangelos; Arias, Andrés; Baris Feldman, Hagit; Belot, Alexandre; Biggs, Catherine; Bogunovic, Dusan; Bolze, Alexandre; Bondarenko, Anastasiia; Bousfiha, Ahmed; Brodin, Petter; Bryceson, Yenan; Bustamante, Carlos; Butte, Manish; Casari, Giorgio; Christodoulou, John; Condino-Neto, Antonio; Constantinescu, Stefan; Cooper, Megan; Dalgard, Clifton; Desai, Murkesh; Drolet, Beth; El Baghdadi, Jamila; Espinosa-Padilla, Sara; Fellay, Jacques; Flores, Carlos; Fragkou, Paraskevi; Franco, José; Froidure, Antoine; Galani, Ioanna; Gregersen, Peter; Grimbacher, Bodo; Haerynck, Filomeen; Hagin, David; Halwani, Rabih; Hammarström, Lennart; Heath, James; Henrickson, Sarah; Hsieh, Elena; Husebye, Eystein; Imai, Kohsuke; Itan, Yuval; Jarvis, Erich; Karamitros, Timokratis; Kisand, Kai; Koltsida, Ourania; Ku, Cheng-Lung; Lau, Yu-Lung; Ling, Yun; Lucas, Carrie; Maniatis, Tom; Mansouri, Davood; Maródi, László; Meyts, Isabelle; Milner, Joshua; Mironska, Kristina; Mogensen, Trine; Morio, Tomohiro; Ng, Lisa; Notarangelo, Luigi; Novelli, Antonio; Novelli, Giuseppe; O'Farrelly, Cliona; Okada, Satoshi; Okamoto, Keisuke; Ozcelik, Tayfun; Pan-Hammarström, Qiang; Pape, Jean; Perez de Diego, Rebeca; Perlin, David; Pesole, Graziano; Planas, Anna; Prando, Carolina; Pujol, Aurora; Quintana-Murci, Lluis; Ramaswamy, Sathishkumar; Rapti, Vasiliki; Renia, Laurent; Resnick, Igor; Rodríguez-Gallego, Carlos; Rovina, Nikoletta; Sancho-Shimizu, Vanessa; Sediva, Anna; Seppänen, Mikko; Shahrooei, Mohammed; Shcherbina, Anna; Slaby, Ondrej; Snow, Andrew; Soler-Palacín, Pere; Spaan, András; Tancevski, Ivan; Tangye, Stuart; Abou Tayoun, Ahmad; Temel, ŞEHİME; Tsiodras, Sotirios; Turvey, Stuart; Uddin, K; Uddin, Mohammed; van de Beek, Diederik; Vinh, Donald; von Bernuth, Horst; Wauters, Joost; Zatz, Mayana; Zawadzki, Pawel; Su, Helen; Casanova, Jean-Laurent; Morel, Pascal; Richard, Pascale; Bonneaudeau, Brigitte; Cannet, Dorothée; Gallian, Pierre; Jeanne, Michel; Perroquin, Magali; Hamzeh-Cognasse, Hind; Cognasse, Fabrice; Tiberghien, Pierre; Nadif, Rachel; Goldberg, Marcel; Ozguler, Anna; Henny, Joseph; Lemonnier, Sylvie; Coeuret-Pellicer, Mireille; Le Got, Stéphane; Zins, Marie; Tzourio, Christophe; Debette, Stéphanie; Dufouil, Carole; Soumaré, Aïcha; Lachaize, Morgane; Fievet, Nathalie; Flaig, Amandine; Martin, Fernando; Mehlal-Sedkaoui, Souad; Sallette, Jérôme; Hernu, Romain; Lina, Bruno; Schwebel, Carole; Wroblewski, Isabelle; Morand, Patrice; Souweine, Bertrand; Boeuf, Benoit; Peigue-Lafeuille, Helene; Darmon, Michael; Patural, Hugues; Pozzetto, Bruno; Quenot, Jean; Colomb, Benoit; Pothier, Pierre; Belot, Alexandre; Abad Arranz, Maria; Aguilar Guisado, Manuela; Escoresca Ortega, Ana; Gallardo Ríos, Rafaela; Merino Díaz, Laura; Del Mar Muñoz Garcia, Maria; Ramírez Duque, Nieves; Romero Vázquez, Gloria; Sánchez Cordero, Maria; Salamanca Rivera, Celia; Niubó, Jordi; Rombauts, Alexander; Navarrete, Nicolás; Romero Oraa, Laura; Palomo, Virginia

doi:10.1084/jem.20220514

Autoantibodies against type I IFNs in patients with critical influenza pneumonia.

Zhang Q., Pizzorno A., Miorin L., Bastard P., Gervais A., Le Voyer T., ...Daha Fazla

The Journal of experimental medicine, cilt.219, sa.11, 2022 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 219 Sayı: 11
Basım Tarihi: 2022
Doi Numarası: 10.1084/jem.20220514
Dergi Adı: The Journal of experimental medicine
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

In an international cohort of 279 patients with hypoxemic influenza pneumonia, we identified 13 patients (4.6%) with autoantibodies neutralizing IFN-alpha and/or -omega, which were previously reported to underlie 15% cases of life-threatening COVID-19 pneumonia and one third of severe adverse reactions to live-attenuated yellow fever vaccine.