Lack of prognostic significance of adiponectin immunohistochemical expression in patients with triplenegative breast cancer


ÇUBUKÇU E., Olmez O. F. , Kanat O., Kabul S., Canhoroz M., Avci N., ...More

WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, vol.18, no.1, pp.34-38, 2014 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.5114/wo.2014.40454
  • Journal Name: WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.34-38
  • Keywords: triple-negative breast cancer, adiponectin, immunohistochemistry, prognosis
  • Bursa Uludag University Affiliated: Yes

Abstract

Introduction: Triple-negative breast cancers (TNBCs) -which lack the expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER-2)-have no established markers that can be used for prognostic stratification. As adiponectin has been previously implicated in a more aggressive phenotype of primary breast cancer, we explored the relation between adiponectin immunohistochemical expression and prognosis in TNBCs.