Objectives: To investigate and describe the effects of Tai Chi exercise program on functional ability and life quality assessments for subjects with senile osteoporosis. Material and Methods: A randomized controlled study was carried out to assess the therapeutic efficacy, of Tai Chi exercises. Forty-four sedentary women (mean age 70.2) with bone mineral density T scores <= -2.5 and less were randomized into 2 groups (Tai Chi group; n= 22 and control group; n= 22) and were enrolled in a 6-months training study. According to the Tai Chi exercise regimen, the hourlong practice icluded a brief warm-up and stretching, a complete long-form Tai Chi for 40 minutes and cool down/relaxation. The control group was instructed not to change their life style for the duration. Patients in both groups were given home-based active range of motion exercises. The groups were evaluated by Nottingham Health Profile (NHP), Short Form Health Survey (SF-36), sensitized Romberg test (SRT), and time sit to stand (TSS). Results: Comparisons of the two groups revealed that the improvement in NHP physical activity score (p= 0.04), NHP tenderness score (p= 0.004), NHP total score (p= 0.02), SF-36 physical function (p= 0.04), SF-36 physical role limitations (p 0.01), SF-36 pain (p= 0.03), SRT eyes open (p= 0.007), SRT eyes closed (p= 0.001) and TSS (p 0.002) were significantly higher in the Tai Chi group than in the control group at the end of 6 months. Conclusion: Tai Chi training is effective in senile osteoporotic subjects to promote functional ability and life quality.