Fast determination of octinoxate and oxybenzone uv filters in swimming pool waters by gas chromatography/mass spectrometry after solid-phase microextraction

Yilmazcan O., Kanakaki C., Izgi B., Rosenberg E.

JOURNAL OF SEPARATION SCIENCE, vol.38, no.13, pp.2286-2297, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 13
  • Publication Date: 2015
  • Doi Number: 10.1002/jssc.201401250
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2286-2297
  • Keywords: Low-pressure gas chromatography, mass spectrometry, Octinoxate, Oxybenzone, Solid-phase microextraction, Swimming pool water, BAR SORPTIVE EXTRACTION, MASS-SPECTROMETRY, ULTRAVIOLET FILTERS, BATHING WATERS, RECENT TRENDS, SAMPLES, BENZOPHENONE, OPTIMIZATION, CONFIGURATIONS, SUNSCREENS
  • Bursa Uludag University Affiliated: Yes


A fast gas chromatography/mass spectrometry method was developed and validated for the analysis of the potential endocrine disrupters octinoxate and oxybenzone in swimming pool water samples based on the solvent-free solid-phase microextraction technique. The low-pressure gas chromatography/mass spectrometry method used for the fast identification of UV filter substances was compared to a conventional method in terms of sensitivity and speed. The fast method proposed resulted in 2 min runs, leading to an eightfold decrease in the total analysis time and a sevenfold improvement in detection limits. The main parameters affecting the solid-phase microextraction process were also studied in detail and the optimized conditions were as follows: fiber coating, polyacrylate; extraction mode, direct immersion; extraction temperature, 25 degrees C; sample volume, 5 mL; extraction time 45 min; pH 6.5. Under the optimized conditions, a linear response was obtained in the concentration range of 0.5-25 mu g/L with correlation coefficients in the range 0.990-0.999. The limits of detection were 0.17-0.29 mu g/L, and the recoveries were 80-83%. Combined method uncertainty was assessed and found to be less than 7% for both analytes for concentrations equal to or higher than 5 mu g/L. Pool water samples were analyzed to demonstrate the applicability of the proposed method. Neither octinoxate nor oxybenzone were detected in the swimming pool water samples at concentrations above the respective limits of detection.