Urinary IL-18: A marker of contrast-induced nephropathy following percutaneous coronary intervention?

Gul C. B. , GÜLLÜLÜ M. , ORAL H. B. , AYDINLAR A. , ÖZ GÜL Ö. , BUDAK F. , ...More

CLINICAL BIOCHEMISTRY, vol.41, pp.544-547, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41
  • Publication Date: 2008
  • Doi Number: 10.1016/j.clinbiochem.2008.01.002
  • Title of Journal : CLINICAL BIOCHEMISTRY
  • Page Numbers: pp.544-547
  • Keywords: contrast agent nephropathy, interleukin-18, urine, biomarker, ACUTE KIDNEY INJURY


Objectives: Contrast-induced nephropathy (CIN) is a complication that is underestimated in clinical practice after cardiac catheterization. Recently, the value of interleukin (IL)-18 as a novel biomarker for the detection of acute renal failure has been highlighted. In the present study, we sought to investigate whether urine IL-18 may be an early diagnostic marker of CIN.