Integrase Strand Transfer Inhibitors (INSTIs) Resistance Mutations in HIV-1 Infected Turkish Patients

Sayan M., Gunduz A., Ersoz G., Inan A., Deveci A., Ozgur G., ...Daha Fazla

HIV CLINICAL TRIALS, cilt.17, sa.3, ss.109-113, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1080/15284336.2016.1153303
  • Dergi Adı: HIV CLINICAL TRIALS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.109-113
  • Anahtar Kelimeler: Hiv-1 Integrase, Integrase Inhibitors, Raltegravir, Elvitegravir, Dolutegravir, Drug Resistance, Dna Sequencing, ANTIRETROVIRAL-NAIVE PATIENTS, NATURAL POLYMORPHISMS, HIV-1, INDIVIDUALS, THERAPY, UPDATE, TURKEY
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Objectives: Integrase strand transfer inhibitor (INSTI) is a new class of antiretroviral (ARV) drugs designed to block the action of the integrase viral enzyme, which is responsible for insertation of the HIV-1 genome into the host DNA. The aim of this study was to evaluate for the first time INSTI resistance mutations in Turkish patients.