Lymphocyte subsets and cytokines in ascitic fluid of decompensated cirrhotic patients with and without spontaneous ascites infection.


Kiyici M., Nak S., Budak F., Gurel S., Oral B., Dolar E., ...More

Journal of gastroenterology and hepatology, vol.21, no.6, pp.963-9, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 6
  • Publication Date: 2006
  • Doi Number: 10.1111/j.1440-1746.2006.04229.x
  • Journal Name: Journal of gastroenterology and hepatology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.963-9
  • Keywords: ascites infections, cytokines, immunology, lymphocytes, SPONTANEOUS BACTERIAL PERITONITIS, LIVER-DISEASE, SOLUBLE FAS, LIPOPOLYSACCHARIDE, REDUCTION, LIGAND, CD4, HCV
  • Bursa Uludag University Affiliated: Yes

Abstract

Background and Aims: Spontaneous ascites infection is a frequently encountered and important complication of decompensated liver cirrhosis. The immune system plays an important role in the development or eradication of this infection. A number of compositional and functional alterations in immune system cells have been demonstrated in cirrhotic patients; however, there is a lack of knowledge about this issue in ascitic infections. The aim of the present study was to evaluate lymphocyte subsets and levels of some ascitic and lymphocytic intracytoplasmic cytokines in decompensated cirrhotic patients with or without spontaneous ascites infection.