Akademik Veri Yönetim Sistemi
Eating Disorders (Living Reference), Patel Vinood,Preedy Victor, Editör, Springer, London/Berlin , London, ss.1-12, 2022
Binge eating disorder (BED) is defined as recurrent and distressing episodes of
excessive food intake despite psychological and physical consequences without
the inappropriate compensatory weight loss behaviors characteristic of bulimia or
anorexia nervosa. Neurobiological underpinnings associated with BED have been
investigated; however, few structural and functional neuroimaging studies to date
have described on the etiology, clinical features, and course of BED. The purpose
of this chapter is to synthesize the recent literature on neuroimaging studies on the
etiology, clinical features, and course of BED, which has been excluded from the
category of “eating disorders not otherwise specified” in DSM-V and has specific
diagnostic criteria. Neuroimaging studies provide evidence including altered
function of prefrontal, insular, and orbitofrontal cortices and the striatum with
altered reward sensitivity and food-related attentional biases. These unique neurobiological changes might be crucial in defining the overlapping neural features
and directing targeted therapies of BED. To disrupt this vicious cycle, novel
research-based studies examining the endogenous DA, NE, 5-HT, opiate, and other systems (e.g., glutamatergic) in the striatum and cortex of individuals with
BED are necessary.