Characteristics Predicting Tuberculosis Risk under Tumor Necrosis Factor-α Inhibitors: Report from a Large Multicenter Cohort with High Background Prevalence.


Kisacik B., Pamuk O. N., Onat A. M., Erer S. B., Hatemi G., Ozguler Y., ...Daha Fazla

The Journal of rheumatology, cilt.43, sa.3, ss.524-9, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.3899/jrheum.150177
  • Dergi Adı: The Journal of rheumatology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.524-9
  • Anahtar Kelimeler: TUMOR NECROSIS FACTOR-A INHIBITORS, TUBERCULOSIS REACTIVATION, ISONIAZID, RHEUMATOID-ARTHRITIS, FACTOR ANTAGONISTS, THERAPY, TNF, MORTALITY, INFECTIONS, TERM
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Objective. Screening strategies for latent tuberculosis (TB) before starting tumor necrosis factor (TNF)-alpha inhibitors have decreased the prevalence of TB among patients who are treated with these agents. However, despite vigilant screening, TB continues to be an important problem, especially in parts of the world with a high background TB prevalence. The aim of this study was to determine the factors related to TB among a large multicenter cohort of patients who were treated with anti-TNF.