Relationship between serum substance P levels and daytime sleepiness in obstructive sleep apnea syndrome

Ursavas, Ahmet; Karadag, MEHMET; Ilcol, Yesim; Burgazlioglu, Basak; Ercan, İLKER; Gozu, R.

doi:10.1378/chest.06-2348

Relationship between serum substance P levels and daytime sleepiness in obstructive sleep apnea syndrome

Ursavas A., Karadag M., Ilcol Y. O., Burgazlioglu B., Ercan İ., Gozu R. O.

CHEST, vol.131, no.5, pp.1400-1405, 2007 (SCI-Expanded)

Publication Type: Article / Article
Volume: 131 Issue: 5
Publication Date: 2007
Doi Number: 10.1378/chest.06-2348
Journal Name: CHEST
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED)
Page Numbers: pp.1400-1405
Keywords: obstructive sleep apnea syndrome, sleepiness, substance P, FIBROMYALGIA, METABOLITES, DEPRESSION, RECEPTORS, SEROTONIN, NEURONS, SAMPLE, BRAIN, RATS, MEN
Bursa Uludag University Affiliated: Yes

Abstract

Objective: We hypothesized that intermittent hypoxia might influence serum substance P levels, and that this effect might in turn contribute in excessive daytime sleepiness (EDS) in patients with obstructive sleep apnea syndrome (OSAS).