JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, vol.139, no.4, pp.691-702, 2013 (Journal Indexed in SCI)
Article / Article
Title of Journal :
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
Colorectal cancer, CK20, MAP3K8, EIF5A, Poor prognosis, Turkish population, INOSINE MONOPHOSPHATE DEHYDROGENASE, GENOMIC HYBRIDIZATION REVEALS, SQUAMOUS-CELL CARCINOMA, INDEPENDENT PREDICTOR, EXPRESSION, CYTOKERATIN-20, EIF-5A2, YOUNG, GENE, AGE
Due to ethnic, genetic and environmental factors, the clinical and molecular characteristics of Turkish colorectal cancer (CRC) patients are different from those of Western populations. The aim of this study was to clarify the relevant alterations of gene expression associated with colorectal carcinogenesis in early-onset patients and to identify specific biomarkers that could provide novel therapeutic molecular targets in this population.